Molecules

Medronate

Target Bone remodellingClass BisphosphonateOther names MDP, methylene diphosphonic acid

0ongoing trials
1radiolabelled forms
1approved products
1,711publications (PubMed)

Structure

Structure from the cited PubChem record (unlabelled ligand, or the labelled form when PubChem only describes that one). Conformer: PubChem (3D conformer computed by PubChem). Rotate with the mouse or a finger.

Properties (PubChem)

Molecular formula
CH6O6P2
Molar mass (g/mol)
176
Exact mass (Da)
175.964
XLogP
-3.3
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
9
InChIKey
MBKDYNNUVRNNRF-UHFFFAOYSA-N
PubChem record
CID 16124 ↗
IUPAC name
phosphonomethylphosphonic acid
SMILES
C(P(=O)(O)O)P(=O)(O)O

Radiolabelled forms

FormUseMolar mass (labelled form)Ongoing trialsMost advanced phaseApproval
[⁹⁹ᵐTc]Tc-medronate Syntheses and QC ↗Imaging306.910—[99mTc] bone scintigraphy (MDP, HMDP, DPD) US EU FR JP

PublicationsAll publications in PubMed ↗

1,711 publications in PubMed for the query below; the most recent:

medronate[tiab] OR "Tc-99m MDP"[tiab] OR "99mTc-MDP"[tiab]

  1. Evaluating the age of rib fractures through (99m)Tc-MDP SPECT strategy based on a machine learning algorithm: a preliminary study Int J Legal Med, 2026
  2. Chondromyxoid Fibroma of the Rib on 99mTc-MDP SPECT/CT Clin Nucl Med, 2026
  3. SAPHO-like bone scintigraphy in diffuse idiopathic skeletal hyperostosis: a case report Front Med (Lausanne), 2026
  4. Detected Huge Urinoma With 99mTc-PSMA Activity on Initial Prostate Cancer Staging Clin Nucl Med, 2026
  5. Inflammation vs. multiple AVN sites: a nuclear medicine evaluation in systemic allergic-immune syndrome - a case report Ann Med Surg (Lond), 2026
  6. Hot-clot Artifacts in the Lung Parenchyma on 18F-CXCR4 PET/CT Clin Nucl Med, 2026
  7. Radiomics of planar Tc-99m methylene diphosphonate bone scintigraphy for pediatric osteomyelitis: a paired infected-contralateral analysis Nucl Med Commun, 2026
  8. Bilateral Knee Osteonecrosis in an Adolescent With Leukemia on Prolonged Corticosteroids: Discordant Femoral-Tibial Findings on Bone Scan SPECT-CT Clin Case Rep, 2026

Sources: PubChem and PubMed (NCBI), ClinicalTrials.gov and CTIS registries, approvals recorded by the atlas. PubChem data as of 28 October 2026.

Cite this page

Medronate. Theranostic Atlas, LaRadiopharmacie.fr. Data as of 27 October 2026. https://theranosticatlas.com/molecule/medronate/ (accessed [date]).

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