Molecules

Flutemetamol

Target AmyloidClass Small molecule (benzothiazole)Other names fluorinated PiB

3ongoing trials
1radiolabelled forms
1approved products
440publications (PubMed)

Structure

Structure from the cited PubChem record (unlabelled ligand, or the labelled form when PubChem only describes that one). Conformer: PubChem (3D conformer computed by PubChem). Rotate with the mouse or a finger.

Properties (PubChem)

Molecular formula
C14H11FN2OS
Molar mass (g/mol)
274.32
Exact mass (Da)
274.0576
XLogP
3.8
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
19
InChIKey
VVECGOCJFKTUAX-UHFFFAOYSA-N
PubChem record
CID 10107393 ↗
IUPAC name
2-[3-fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
SMILES
CNC1=C(C=C(C=C1)C2=NC3=C(S2)C=C(C=C3)O)F

Radiolabelled forms

FormUseMolar mass (labelled form)Ongoing trialsMost advanced phaseApproval
[¹⁸F]flutemetamol Syntheses and QC ↗Imaging273.323Phase 2Amyvid, Vizamyl, Neuraceq US EU FR JP

Ongoing trials · 3Open in the radar →

Atlas trials whose studied drug or title names this vector, with this radionuclide.

TrialPhaseStatusSponsorCountries
Amyloid tracersNCT07873463 · Alzheimer's disease and cognitive disordersPhase 2Not yet recruitingGE Healthcare1
Amyloid tracersNCT07012993 · Alzheimer's disease and cognitive disordersPhase 2RecruitingAkiva Mintz1
Amyloid tracers2024-519961-23-00 · Alzheimer's disease and cognitive disordersPhase 1Not yet recruitingBarcelonabeta Brain Research Center1
Other trials listing it among the interventions (comparator, associated scan) · 4
Amyloid tracersNCT03068442 · Alzheimer's disease and cognitive disordersPhase 2Active, not recruitingScott Mcnally1
Amyloid tracers2025-522348-42-00 · OtherPhase 2RecruitingAmsterdam UMC Stichting1
Amyloid tracers2023-503705-10-00 · Alzheimer's disease and cognitive disordersPhase 1RecruitingDeutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V.1
BioFINDER2 · Amyloid tracersNCT03174938 · Alzheimer's disease and cognitive disordersNo phaseRecruitingSkane University Hospital1

PublicationsAll publications in PubMed ↗

440 publications in PubMed for the query below; the most recent:

flutemetamol[tiab]

  1. Decreased awareness of cognitive decline is associated with multimodal Alzheimer's disease biomarkers in cognitively unimpaired individuals Neurobiol Aging, 2026
  2. Impact of adjunctive quantitative analysis on visual interpretation of amyloid PET: a multiple tracer, multicentre study Eur Radiol, 2026
  3. Low Uptake of [18F]Flutemetamol in the Mouse Brain Prevents Non-invasive Quantification of Myelin Mol Pharm, 2026
  4. From image reconstruction to clinical prognosis: A comprehensive analysis of centiloid-based amyloid PET assessment Eur J Nucl Med Mol Imaging, 2026
  5. Analysis of the off-target interaction of amyloid PET tracers with human brain sulfotransferases Neurol Sci, 2026
  6. Comparison of Expert Reads Versus Local Clinical Reads of Amyloid PET Scans in the IDEAS Study J Nucl Med, 2026
  7. Amyloid-β PET Radioligands in Alzheimer's Disease: From Plaque Detection to Biomarker-Guided Patient Stratification and Therapeutic Monitoring Mol Diagn Ther, 2026
  8. Perceptual-phase eye-tracking during figure copying is associated with amyloid-β PET positivity in mild cognitive impairment J Alzheimers Dis, 2026

Sources: PubChem and PubMed (NCBI), ClinicalTrials.gov and CTIS registries, approvals recorded by the atlas. PubChem data as of 28 October 2026.

Cite this page

Flutemetamol. Theranostic Atlas, LaRadiopharmacie.fr. Data as of 27 October 2026. https://theranosticatlas.com/molecule/flutemetamol/ (accessed [date]).

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