Ongoing clinical trials and approved products targeting TSPO (neuroinflammation), in radioligand therapy and PET/SPECT imaging. Data as of 26 October 2026.
| Trial | Phase | Status | Sponsor | Countries |
|---|---|---|---|---|
| TSPO tracers2023-504181-38-00 · Psychiatry and addiction | Phase 3 | Recruiting | Institut National De La Sante Et De La Recherche Medicale | 1 |
| INFINITE · TSPO tracersNCT07583147 · Neuroinflammation and multiple sclerosis | Phase 2 | Not yet recruiting | University Hospital, Toulouse | 1 |
| MAPET · TSPO tracersNCT02649985 · Alzheimer's disease and cognitive disorders | Phase 2 | Recruiting | Brigham and Women's Hospital | 1 |
| TSPO tracersNCT05128903 · Neuroinflammation and multiple sclerosis | Phase 2 | Active, not recruiting | St. Jude Children's Research Hospital | 1 |
| EAI-714 · TSPO tracersNCT07488117 · Neuroinflammation and multiple sclerosis | Phase 2 | Recruiting | University Hospital, Toulouse | 1 |
| ART · TSPO tracersNCT05586581 · Alzheimer's disease and cognitive disorders | Phase 2 | Recruiting | Yale University | 1 |
| TSPO tracersNCT03705715 · Psychiatry and addiction | Phase 1 | Recruiting | The University of Texas Health Science Center, Houston | 1 |
| TSPO tracersNCT03759522 · Neuroinflammation and multiple sclerosis | Phase 1 | Recruiting | University of Alabama at Birmingham | 1 |
| TSPO tracersNCT06289582 · Parkinson's disease and parkinsonian syndromes | Phase 1 | Recruiting | University of Alabama at Birmingham | 1 |
| TSPO tracersNCT03999164 · Epilepsy | Phase 1 | Active, not recruiting | University of California, Davis | 1 |
| TSPO tracersNCT04274998 · Alzheimer's disease and cognitive disorders | Phase 1 | Active, not recruiting | University of Pennsylvania | 1 |
| CT1-DAP001 · [18F]FEPPANCT06482268 · Parkinson's disease and parkinsonian syndromes | Phase 1 | Recruiting | University of California, San Diego | 1 |
| INFLANET · TSPO tracersNCT06280742 · Neuroinflammation and multiple sclerosis | No phase | Recruiting | Assistance Publique - Hôpitaux de Paris | 1 |
| TSPO tracersNCT06851143 · Other | No phase | Not yet recruiting | Xijing Hospital | 0 |
| TSPO tracersNCT06113705 · Brain (glioma, medulloblastoma…) | No phase | Recruiting | Istituto Clinico Humanitas | 1 |
| [18F]FEPPANCT02945774 · Alzheimer's disease and cognitive disorders | No phase | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 1 |
| ICARUS · TSPO tracersNCT04412187 · Stroke and trauma | No phase | Recruiting | Martin Dichgans | 1 |
TSPO (neuroinflammation). Theranostic Atlas, LaRadiopharmacie.fr. Data as of 26 October 2026. https://theranosticatlas.com/target/tspo-neuroinflammation/ (accessed [date]).
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