Myocardial perfusion

Ongoing clinical trials and approved products targeting Myocardial perfusion, in radioligand therapy and PET/SPECT imaging. Data as of 26 October 2026.

0ongoing therapy trials

15ongoing imaging trials

2approved products

Target note

Full name: Myocardial perfusion
Nature: Coronary blood flow tracers: cations (⁸²Rb, ²⁰¹Tl), ammonia, labeled water, mitochondrial complex I inhibitors (flurpiridaz), lipophilic ⁹⁹ᵐTc complexes.
Normal expression: Myocardium, liver and bowel (interfering with the inferior wall on SPECT).
Value: Diagnosis and prognosis of coronary artery disease; PET allows quantification of absolute blood flow and coronary flow reserve.
Approaches: PET: ⁸²Rb, [13N]ammonia, [15O]water, [18F]flurpiridaz (Flyrcado); SPECT: [99mTc]sestamibi, [99mTc]tetrofosmin, ²⁰¹Tl.
Indications explored: Ischemic heart disease, assessment of the microcirculation.
Points of caution: Attenuation artifacts (breast, diaphragm) on SPECT; ⁸²Rb and ¹³N require a generator or a nearby cyclotron.

Approved products

PET perfusion (Cardiogen, Ruby-Fill, ¹³N-ammonia, Flyrcado)⁸²Rb, [13N]ammoniac, [18F]flurpiridaz	Bracco, Jubilant, multiples, GE HealthCare	marketed	US EU FR
SPECT perfusion (sestamibi, tetrofosmin, thallium)[99mTc]sestamibi, [99mTc]tetrofosmin, ²⁰¹Tl	Multiples	marketed	US EU FR JP

Ongoing imaging trials · 15Open in the radar →

Trial	Phase	Status	Sponsor	Countries
Myocardial perfusion tracersNCT05134012 · Ischemic heart disease	Phase 3	Active, not recruiting	MedTrace Pharma A/S	6
Myocardial perfusion tracersNCT07439133 · Ischemic heart disease	Phase 3	Recruiting	Sinotau Pharmaceutical Group	1
Myocardial perfusion tracers2024-518706-41-01 · Ischemic heart disease	Phase 3	Not yet recruiting	Vaestra Goetalandsregionen	1
Myocardial perfusion tracersNCT01899833 · Ischemic heart disease	Phase 2	Not yet recruiting	Cell>Point LLC	1
Myocardial perfusion tracersNCT07284576 · Ischemic heart disease	Phase 2	By invitation	Akiva Mintz	1
Myocardial perfusion tracersNCT05583721 · Ischemic heart disease	Phase 2	Recruiting	St. Jude Children's Research Hospital	1
Myocardial perfusion tracersNCT07761910 · Other	Phase 2	Recruiting	Indiana University	1
Myocardial perfusion tracersNCT02744053 · Other	Phase 1	Active, not recruiting	M.D. Anderson Cancer Center	1
Myocardial perfusion tracersNCT05042687 · Other	No phase	Recruiting	M.D. Anderson Cancer Center	1
Myocardial perfusion tracersNCT06980194 · Ischemic heart disease	No phase	Not yet recruiting	China National Center for Cardiovascular Diseases	0
Myocardial perfusion tracersNCT03275584 · Other	No phase	Recruiting	Centre hospitalier de l'Université de Montréal (CHUM)	1
Dyna-MI · Myocardial perfusion tracersNCT05940285 · Ischemic heart disease	No phase	Active, not recruiting	Nantes University Hospital	1
Myocardial perfusion tracersNCT06058650 · Other	No phase	Recruiting	Mayo Clinic	1
Myocardial perfusion tracersNCT03935984 · Hyperparathyroidism	No phase	Recruiting	Joseph Sferra	1
Myocardial perfusion tracersNCT02324387 · Other	No phase	Active, not recruiting	M.D. Anderson Cancer Center	1

Cite this page

Myocardial perfusion. Theranostic Atlas, LaRadiopharmacie.fr. Data as of 26 October 2026. https://theranosticatlas.com/target/myocardial-perfusion/ (accessed [date]).

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