Labeled leukocytes

Ongoing clinical trials and approved products targeting Labeled leukocytes, in radioligand therapy and PET/SPECT imaging. Data as of 26 October 2026.

0ongoing therapy trials
0ongoing imaging trials
2approved products

Target note

Full name
Labeled autologous leukocytes
Nature
The patient's leukocytes are labeled in vitro, then reinjected, and migrate to sites of infection.
Normal expression
Spleen, liver, bone marrow.
Value
The reference for bone, joint and prosthetic infection.
Approaches
[99mTc]HMPAO-leukocytes, [111In]oxine-leukocytes.
Indications explored
Prosthetic infections, osteomyelitis, endocarditis, inflammatory bowel diseases.
Points of caution
Blood handling (dedicated radiopharmacy); physiological marrow uptake to be distinguished from infection.

Approved products

Labeled leukocytes ([99mTc]exametazime, [111In]oxine)[99mTc]exametazime, [111In]oxineMultiplesmarketed (national authorisations)US EU FR
Scintimun[99mTc]besilesomabTelix InnovationsmarketedEU FR

Cite this page

Labeled leukocytes. Theranostic Atlas, LaRadiopharmacie.fr. Data as of 26 October 2026. https://theranosticatlas.com/target/labeled-leukocytes/ (accessed [date]).

A monitoring tool with no regulatory value: check every item at its source.