Ongoing clinical trials and approved products targeting Amino acid transport, in radioligand therapy and PET/SPECT imaging. Data as of 26 October 2026.
| Axumin[18F]fluciclovine | Blue Earth Diagnostics | marketed | US EU FR JP |
| Pixclara[18F]floretyrosine (FET) | Telix | approved (2026) | US |
| Trial | Phase | Status | Sponsor | Countries |
|---|---|---|---|---|
| [18F]FETNCT07698457 · Brain (glioma, medulloblastoma…) | Phase 3 | Not yet recruiting | Primo Biotechnology Co., Ltd | 1 |
| [18F]fluciclovineNCT06159335 · Solid tumors (multiple indications) | Phase 3 | Recruiting | University of Wisconsin, Madison | 1 |
| [18F]fluciclovine2024-517095-38-00 · Myeloma | Phase 3 | Recruiting | Oslo University Hospital HF | 1 |
| Labeled amino acids (FSPG, glutamine, tryptophan)NCT07735819 · Brain (glioma, medulloblastoma…) | Phase 2 | Not yet recruiting | Barbara Ann Karmanos Cancer Institute | 1 |
| GABLE · [18F]fluciclovineNCT06319027 · Brain (glioma, medulloblastoma…) | Phase 2 | Recruiting | ECOG-ACRIN Cancer Research Group | 1 |
| [11C]methionineNCT00840047 · Neuroblastoma | Phase 2 | Active, not recruiting | St. Jude Children's Research Hospital | 1 |
| CONCORDANT · [18F]fluciclovineNCT05554302 · Solid tumors (multiple indications) | Phase 2 | Recruiting | Baptist Health South Florida | 1 |
| FET-PIT · [18F]FETNCT07360548 · Other | Phase 2 | Not yet recruiting | University Hospital, Lille | 1 |
| FET PET in HGG · [18F]FETNCT06172595 · Brain (glioma, medulloblastoma…) | Phase 2 | Recruiting | Singapore General Hospital | 1 |
| Labeled amino acids (FSPG, glutamine, tryptophan)NCT02379377 · Liver (HCC) | Phase 1 | Active, not recruiting | M.D. Anderson Cancer Center | 1 |
| [18F]fluciclovineNCT04689048 · Solid tumors (multiple indications) | Phase 1 | Recruiting | Baptist Health South Florida | 1 |
| Labeled amino acids (FSPG, glutamine, tryptophan)NCT05452889 · Other | Phase 1 | Recruiting | Stephen Y. Chan | 1 |
| FACILITATE · [18F]fluciclovineNCT06048094 · Solid tumors (multiple indications) | Phase 1 | Recruiting | Baptist Health South Florida | 1 |
| [18F]FETNCT07456878 · Other | Phase 1 | Recruiting | Mayo Clinic | 1 |
| [18F]fluciclovineNCT05555550 · Brain (glioma, medulloblastoma…) | Phase 1 | Recruiting | Children's Hospital of Philadelphia | 1 |
| [18F]fluciclovineNCT06062745 · Prostate – mCRPC | Phase 1 | Recruiting | Brigham and Women's Hospital | 1 |
| Labeled amino acids (FSPG, glutamine, tryptophan)NCT02390635 · Leukemia / transplant conditioning | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 1 |
| Labeled amino acids (FSPG, glutamine, tryptophan)NCT01697930 · Lymphoma | Phase 1 | Active, not recruiting | Memorial Sloan Kettering Cancer Center | 1 |
| [18F]fluciclovineNCT06055790 · Other | Phase 1 | Recruiting | University of Arizona | 1 |
| Labeled amino acids (FSPG, glutamine, tryptophan)NCT07116486 · Liver (HCC) | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 1 |
| GBM · [18F]fluciclovineNCT06613841 · Brain (glioma, medulloblastoma…) | Phase 1 | Recruiting | Abramson Cancer Center at Penn Medicine | 1 |
| [18F]F-GLN · Labeled amino acids (FSPG, glutamine, tryptophan)NCT03863457 · Breast | Phase 1 | Recruiting | Abramson Cancer Center at Penn Medicine | 1 |
| [18F]fluciclovineNCT05553041 · Brain (glioma, medulloblastoma…) | Phase 1 | Recruiting | Children's Hospital of Philadelphia | 1 |
| Labeled amino acids (FSPG, glutamine, tryptophan)NCT05676489 · Healthy volunteers (dosimetry, biodistribution) | Phase 1 | Not yet recruiting | University of Alabama at Birmingham | 1 |
| [18F]FETNCT05632562 · Brain (glioma, medulloblastoma…) | Phase 1 | Recruiting | University of Alabama at Birmingham | 1 |
| [18F]fluciclovineNCT07569926 · Prostate – localised / recurrence | No phase | Recruiting | Blue Earth Diagnostics | 1 |
| FET-POPPING · [18F]FETNCT06480721 · Brain (glioma, medulloblastoma…) | No phase | Not yet recruiting | Veerle Ruijters | 1 |
| [18F]FETNCT07475390 · Brain (glioma, medulloblastoma…) | No phase | Active, not recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 1 |
| FIND · [18F]FETNCT07108244 · Adrenal | No phase | By invitation | University Hospital, Basel, Switzerland | 2 |
| FET-pit-PET · [18F]FETNCT06584123 · Other | No phase | Recruiting | University of Cambridge | 1 |
| [18F]fluciclovineNCT05722925 · Prostate – localised / recurrence | No phase | Active, not recruiting | OHSU Knight Cancer Institute | 1 |
| [18F]fluciclovineNCT06706921 · Prostate – mCRPC | No phase | Recruiting | VA Greater Los Angeles Healthcare System | 1 |
Amino acid transport. Theranostic Atlas, LaRadiopharmacie.fr. Data as of 26 October 2026. https://theranosticatlas.com/target/amino-acid-transport/ (accessed [date]).
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